For weekend travel, fly from San Diego to Cabo San Lucas for $265 roundtrip on American.
I found seats departing San Diego SAN on Friday, January 25, returning from Cabo San Lucas SJD on Monday, January 28. Flights connect in Phoenix PHX.
Weekend flights to Mexico are usually much more expensive than flying mid-week. Take advantage of this hand-picked weekend deal to enjoy a few days of tacos and tequila in one of Mexico's most famous beach resorts.
Don't worry about extra restrictions since this is a Main Cabin Economy fare on American, which will include advanced seat selection and the ability to upgrade or make ticket changes for a fee. You'll find a slightly lower $235 roundtrip fare if you don't mind those restrictions.
The downfall of this price is that it does require a connection in Phoenix PHX, but taking the short hop will save you hundreds of dollars compared to nonstop flights for weekend travel on other airlines. Of course, if you can fly during the middle of the week, you'll find even lower fares.
Need a room in Cabo? Here's what's available for the mentioned weekend dates on Hotelwatchdog.
For more weekend travel deals from your city, make sure to have a look at our new and improved Weekender search tool.