Searching British Airways, we found seats departing BOS on Tuesday, November 20, returning from FCO on Friday, November 30. Flights connect via Dublin.
Other dates are also available for travel throughout November and into early December.
Slightly lower fares ($40 to $50 less) are available for those who prefer to stay longer, or don't mind overnight connections in Dublin.
See our Boston BOS fare listings for a complete look at current finds.
Need a room in Rome? Here's what we've found for the above dates on Hotelwatchdog.