Fly nonstop from Boston to Rome for $474 round-trip on Alitalia.
Seen below, we found seats departing BOS on April 3, returning from FCO on April 12.
Other dates are also available for travel for departures in March/April, with slightly higher fares for late spring/summer.
See our fare details for booking info.
Need a room in Rome? Here's what's available for the above dates on Hotelwatchdog.