Fly from Chicago to Panama City for $237 round-trip on American Airlines.

Seen below, we found seats departing ORD on Wednesday, October 12, returning from PTY on Monday, October 17. Flights connect via Miami, with most returning dates require an overnight stay in Miami.

Other dates are available for departures through December 15.

See our fare details for booking info.

Need a room in Panama City? Here's a look at what's available for the above dates on Hotelwatchdog.