Chicago to Santa Cruz, Bolivia $286 Round-Trip on Copa

Fly from Chicago to Santa Cruz de la Sierra, Bolivia for $286 round-trip on Copa.

Searching Orbitz, we found seats departing ORD on Thursday, May 5, returning from VVI on Thursday, May 12. Flights connect via Panama City PTY.

Other dates are available for travel in winter/spring through May 26.

See our fare details for booking info.

Need a room in Santa Cruz? Here's what's available for the above dates on Hotelwatchdog.