Fly from Chicago to Santo Domingo, DR for $320 round-trip on Aeromexico.

Aeromexico's new service to Santo Domingo begins in mid-March, with flights connecting via Mexico City MEX.

Some itineraries may involve lengthy connections via Mexico City, allowing you plenty of time to explore.

Searching Orbitz, we found seats departing ORD on Thursday, June 9, returning from SDQ on Monday, June 13.

Other dates are available for travel from March through early June.

See our fare details for booking info.

Need a room in Santo Domingo? Here's what's available for the above dates on Hotelwatchdog.

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