Cheap flights to Des Moines, Iowa (DSM)

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$98 RT
St. Louis, MO (STL) No min. stay.. Fare can be bought one-way for half the lowest roundtrip... (Southwest) See all details »
$142 RT
St. Petersburg, FL (PIE) Lowest fare found for travel within the next 30 days. (Allegiant) See all details »
$148 RT
Denver, CO (DEN) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$157 RT
Las Vegas, NV (LAS) Lowest fare found for travel within the next 30 days. (Allegiant) See all details »
$176 RT
St. Louis, MO (STL) Lowest fare found for travel within the next 30 days. (American) See all details »
$182 RT
Orlando, FL (SFB) Lowest fare found for travel within the next 30 days. (Allegiant) See all details »
$184 RT
Phoenix, AZ (PHX) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$198 RT
Los Angeles, CA (LAX) Lowest fare found for travel within the next 30 days. (Allegiant) See all details »
$202 RT
Minneapolis, MN (MSP) Lowest fare found for travel within the next 30 days. (United) See all details »
$210 RT
Dallas, TX (DFW) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$212 RT
Salt Lake City, UT (SLC) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$224 RT
Detroit, MI (DTW) Lowest fare found for travel within the next 30 days. (United) See all details »
$230 RT
Houston, TX (IAH) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$241 RT
Atlanta, GA (ATL) Lowest fare found for travel within the next 30 days. (United) See all details »
$264 RT
San Diego, CA (SAN) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$264 RT
San Francisco, CA (SFO) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$272 RT
New York City, NY (LGA) Lowest fare found for travel within the next 30 days. (United) See all details »
$275 RT
Washington, D.C. (DCA) Lowest fare found for travel within the next 30 days. (United) See all details »
$276 RT
Washington, D.C. (IAD) Lowest fare found for travel within the next 30 days. (United) See all details »
$282 RT
Oklahoma City, OK (OKC) Lowest fare found for travel within the next 30 days. (United, American) See all details »
$302 RT
Indianapolis, IN (IND) Lowest fare found for travel within the next 30 days. (United, American) See all details »
$303 RT
Seattle, WA (SEA) Lowest fare found for travel within the next 30 days. (United, American) See all details »
$310 RT
Nashville, TN (BNA) Lowest fare found for travel within the next 30 days. (United) See all details »
$314 RT
Chicago, IL (ORD) Lowest fare found for travel within the next 30 days. (American) See all details »
$314 RT
Portland, OR (PDX) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$316 RT
Las Vegas, NV (LAS) No min. stay.. Fare can be bought one-way for half the lowest roundtrip... (Southwest) See all details »
$317 RT
Baltimore, MD (BWI) Lowest fare found for travel within the next 30 days. (United) See all details »
$317 RT
Philadelphia, PA (PHL) Lowest fare found for travel within the next 30 days. (United) See all details »
$320 RT
Pittsburgh, PA (PIT) Lowest fare found for travel within the next 30 days. (American) See all details »
$320 RT
Cleveland, OH (CLE) Lowest fare found for travel within the next 30 days. (American) See all details »
$322 RT
Columbus, OH (CMH) Lowest fare found for travel within the next 30 days. (United) See all details »
$333 RT
New Orleans, LA (MSY) Lowest fare found for travel within the next 30 days. (American) See all details »
$333 RT
Charlotte, NC (CLT) Lowest fare found for travel within the next 30 days. (United, American) See all details »
$334 RT
Grand Rapids, MI (GRR) Lowest fare found for travel within the next 30 days. (United, American) See all details »
$335 RT
Austin, TX (AUS) Lowest fare found for travel within the next 30 days. (American) See all details »
$335 RT
Raleigh, NC (RDU) Lowest fare found for travel within the next 30 days. (United) See all details »
$336 RT
Houston, TX (HOU) Lowest fare found for travel within the next 30 days. (American) See all details »
$336 RT
San Antonio, TX (SAT) Lowest fare found for travel within the next 30 days. (United, American) See all details »
$336 RT
Richmond, VA (RIC) Lowest fare found for travel within the next 30 days. (United) See all details »
$343 RT
Boston, MA (BOS) Lowest fare found for travel within the next 30 days. (United) See all details »
$343 RT
Orlando, FL (MCO) Lowest fare found for travel within the next 30 days. (United) See all details »
$343 RT
Tampa, FL (TPA) Lowest fare found for travel within the next 30 days. (United) See all details »
$344 RT
Tucson, AZ (TUS) Lowest fare found for travel within the next 30 days. (United, American) See all details »
$344 RT
Hartford, CT (BDL) Lowest fare found for travel within the next 30 days. (United) See all details »
$361 RT
Jacksonville, FL (JAX) Lowest fare found for travel within the next 30 days. (American) See all details »
$364 RT
West Palm Beach, FL (PBI) Lowest fare found for travel within the next 30 days. (American) See all details »
$368 RT
Chicago, IL (MDW) Lowest fare found for travel within the next 30 days. (Delta) See all details »
$369 RT
Ft. Lauderdale, FL (FLL) Lowest fare found for travel within the next 30 days. (American) See all details »
$376 RT
New York City, NY (JFK) Lowest fare found for travel within the next 30 days. (American) See all details »
$383 RT
Newark, NJ (EWR) Lowest fare found for travel within the next 30 days. (United) See all details »
$385 RT
Ft. Myers, FL (RSW) Lowest fare found for travel within the next 30 days. (American) See all details »
$388 RT
San Jose, CA (SJC) Lowest fare found for travel within the next 30 days. (American) See all details »
$398 RT
Oakland, CA (OAK) Lowest fare found for travel within the next 30 days. (American) See all details »
$402 RT
Ontario, CA (ONT) Lowest fare found for travel within the next 30 days. (American) See all details »
$414 RT
Burbank, CA (BUR) Lowest fare found for travel within the next 30 days. (American) See all details »
$433 RT
Dallas, TX (DAL) Lowest fare found for travel within the next 30 days. (Delta) See all details »
$445 RT
Spokane, WA (GEG) Lowest fare found for travel within the next 30 days. (American) See all details »
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