Cheap flights to Des Moines, Iowa (DSM)

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$321 RT
Atlanta, GA (ATL) Lowest fare found for travel within the next 30 days. (Delta) See all details »
$312 RT
Austin, TX (AUS) Lowest fare found for travel within the next 30 days. (United, Delta, American) See all details »
$268 RT
Baltimore, MD (BWI) Lowest fare found for travel within the next 30 days. (American) See all details »
$304 RT
Boston, MA (BOS) Lowest fare found for travel within the next 30 days. (United) See all details »
$282 RT
Burbank, CA (BUR) Lowest fare found for travel within the next 30 days. (United, Delta) See all details »
$343 RT
Charlotte, NC (CLT) Lowest fare found for travel within the next 30 days. (American) See all details »
$230 RT
Chicago, IL (MDW) Lowest fare found for travel within the next 30 days. (Delta) See all details »
$168 RT
Chicago, IL (ORD) Lowest fare found for travel within the next 30 days. (American) See all details »
$298 RT
Cleveland, OH (CLE) Lowest fare found for travel within the next 30 days. (United, Delta, American) See all details »
$298 RT
Columbus, OH (CMH) Lowest fare found for travel within the next 30 days. (United, Delta, American) See all details »
$367 RT
Dallas, TX (DAL) Lowest fare found for travel within the next 30 days. (Delta) See all details »
$372 RT
Dallas, TX (DFW) Lowest fare found for travel within the next 30 days. (Delta) See all details »
$228 RT
Denver, CO (DEN) Travel this weekend. (United) See all details »
$228 RT
Denver, CO (DEN) Lowest fare found for travel within the next 30 days. (United) See all details »
$341 RT
Detroit, MI (DTW) Lowest fare found for travel within the next 30 days. (Delta) See all details »
$341 RT
Ft. Lauderdale, FL (FLL) Lowest fare found for travel within the next 30 days. (American) See all details »
$312 RT
Ft. Myers, FL (RSW) Lowest fare found for travel within the next 30 days. (American) See all details »
$298 RT
Grand Rapids, MI (GRR) Lowest fare found for travel within the next 30 days. (United, Delta, American) See all details »
$318 RT
Hartford, CT (BDL) Lowest fare found for travel within the next 30 days. (United, Delta) See all details »
$278 RT
Houston, TX (IAH) Travel this weekend. (United) See all details »
$278 RT
Houston, TX (HOU) Lowest fare found for travel within the next 30 days. (United) See all details »
$335 RT
Houston, TX (IAH) Lowest fare found for travel within the next 30 days. (United) See all details »
$254 RT
Indianapolis, IN (IND) Lowest fare found for travel within the next 30 days. (United, Delta, American) See all details »
$301 RT
Jacksonville, FL (JAX) Lowest fare found for travel within the next 30 days. (American) See all details »
$312 RT
Las Vegas, NV (LAS) No min. stay.. Fare can be bought one-way for half the lowest roundtrip... (Southwest) See all details »
$224 RT
Las Vegas, NV (LAS) Lowest fare found for travel within the next 30 days. (Allegiant) See all details »
$258 RT
Los Angeles, CA (LAX) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$242 RT
Mesa, AZ (AZA) Lowest fare found for travel within the next 30 days. (Allegiant) See all details »
$197 RT
Minneapolis, MN (MSP) Lowest fare found for travel within the next 30 days. (Delta) See all details »
$248 RT
Nashville, TN (BNA) Lowest fare found for travel within the next 30 days. (United, American) See all details »
$249 RT
New Orleans, LA (MSY) Lowest fare found for travel within the next 30 days. (American) See all details »
$338 RT
New York City, NY (JFK) Lowest fare found for travel within the next 30 days. (Delta) See all details »
$321 RT
New York City, NY (LGA) Lowest fare found for travel within the next 30 days. (Delta) See all details »
$246 RT
Newark, NJ (EWR) Lowest fare found for travel within the next 30 days. (American) See all details »
$334 RT
Oakland, CA (OAK) Lowest fare found for travel within the next 30 days. (American) See all details »
$262 RT
Oklahoma City, OK (OKC) Lowest fare found for travel within the next 30 days. (United, Delta, American) See all details »
$275 RT
Ontario, CA (ONT) Lowest fare found for travel within the next 30 days. (American) See all details »
$292 RT
Orlando, FL (MCO) Lowest fare found for travel within the next 30 days. (American) See all details »
$309 RT
Philadelphia, PA (PHL) Lowest fare found for travel within the next 30 days. (American) See all details »
$213 RT
Phoenix, AZ (PHX) Lowest fare found for travel within the next 30 days. (American) See all details »
$293 RT
Pittsburgh, PA (PIT) Lowest fare found for travel within the next 30 days. (American) See all details »
$274 RT
Portland, OR (PDX) Lowest fare found for travel within the next 30 days. (Delta) See all details »
$310 RT
Raleigh, NC (RDU) Lowest fare found for travel within the next 30 days. (American) See all details »
$310 RT
Richmond, VA (RIC) Lowest fare found for travel within the next 30 days. (American) See all details »
$344 RT
Sacramento, CA (SMF) Lowest fare found for travel within the next 30 days. (United, Delta, American) See all details »
$361 RT
Salt Lake City, UT (SLC) Lowest fare found for travel within the next 30 days. (Delta, Frontier) See all details »
$312 RT
San Antonio, TX (SAT) Lowest fare found for travel within the next 30 days. (United, Delta, American) See all details »
$344 RT
San Diego, CA (SAN) Lowest fare found for travel within the next 30 days. (United, Delta, American) See all details »
$322 RT
San Francisco, CA (SFO) Lowest fare found for travel within the next 30 days. (American) See all details »
$334 RT
San Jose, CA (SJC) Lowest fare found for travel within the next 30 days. (United, Delta, American) See all details »
$270 RT
Seattle, WA (SEA) Lowest fare found for travel within the next 30 days. (United, Delta, American) See all details »
$318 RT
Spokane, WA (GEG) Lowest fare found for travel within the next 30 days. (United, Delta) See all details »
$108 RT
St. Louis, MO (STL) No min. stay.. Fare can be bought one-way for half the lowest roundtrip... (Southwest) See all details »
$144 RT
St. Louis, MO (STL) Lowest fare found for travel within the next 30 days. (Delta, American) See all details »
$190 RT
St. Petersburg, FL (PIE) Lowest fare found for travel within the next 30 days. (Allegiant) See all details »
$318 RT
Tampa, FL (TPA) Lowest fare found for travel within the next 30 days. (United, Delta, American) See all details »
$318 RT
Tucson, AZ (TUS) Lowest fare found for travel within the next 30 days. (United, American) See all details »
$270 RT
Washington, D.C. (IAD) Lowest fare found for travel within the next 30 days. (United, Delta) See all details »
$253 RT
Washington, D.C. (DCA) Lowest fare found for travel within the next 30 days. (American) See all details »
$341 RT
West Palm Beach, FL (PBI) Lowest fare found for travel within the next 30 days. (American) See all details »
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