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Cheap flights to Des Moines, Iowa (DSM)

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$322 RT
Albuquerque, NM (ABQ) Fall/Winter travel. No min. stay (American) See all details »
$424 RT
Amarillo, TX (AMA) Fall/Winter travel. No min. stay (American) See all details »
$346 RT
Atlanta, GA (ATL) Non-Stop Flights (Delta) See all details »
$298 RT
Atlanta, GA (ATL) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$267 RT
Austin, TX (AUS) Lowest fare found for travel within the next 30 days. (US Airways, United) See all details »
$249 RT
Baltimore, MD (BWI) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$402 RT
Baton Rouge, LA (BTR) Fall/Winter travel. No min. stay (American) See all details »
$322 RT
Birmingham, AL (BHM) Fall/Winter travel. No min. stay (American) See all details »
$331 RT
Boston, MA (BOS) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$362 RT
Buffalo, NY (BUF) Fall/Winter travel. No min. stay (American) See all details »
$286 RT
Charlotte, NC (CLT) Lowest fare found for travel within the next 30 days. (Delta) See all details »
$188 RT
Chicago, IL (MDW) Fall/Winter travel. No min. stay. Fare can be bought one-way for half t... (Southwest) See all details »
$187 RT
Chicago, IL (ORD) Lowest fare found for travel within the next 30 days. (United, American) See all details »
$362 RT
Corpus Christi, TX (CRP) Fall/Winter travel. No min. stay (American) See all details »
$267 RT
Dallas, TX (DFW) Non-Stop Flights. No min. stay (American) See all details »
$267 RT
Dallas, TX (DFW) Lowest fare found for travel within the next 30 days. (American) See all details »
$228 RT
Denver, CO (DEN) Nonstop; Travel this weekend (United) See all details »
$135 RT
Denver, CO (DEN) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$355 RT
Detroit, MI (DTW) Non-Stop Flights (Delta) See all details »
$362 RT
El Paso, TX (ELP) Fall/Winter travel. No min. stay (American) See all details »
$310 RT
Ft. Myers, FL (RSW) Fall/Winter travel. No min. stay (American) See all details »
$352 RT
Hartford, CT (BDL) No min. stay. Fare can be bought one-way for half the lowest roundtrip ... (Southwest) See all details »
$276 RT
Houston, TX (IAH) Nonstop; Travel this weekend (United) See all details »
$276 RT
Houston, TX (IAH) Lowest fare found for travel within the next 30 days. (United) See all details »
$382 RT
Huntsville, AL (HSV) Fall/Winter travel. No min. stay (American) See all details »
$362 RT
Jacksonville, FL (JAX) Fall/Winter travel. No min. stay (American) See all details »
$254 RT
Las Vegas, NV (LAS) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$362 RT
Lexington, KY (LEX) Fall/Winter travel. No min. stay (American) See all details »
$294 RT
Little Rock, AR (LIT) Fall/Winter travel. No min. stay (American) See all details »
$278 RT
Los Angeles, CA (LAX) Lowest fare found for travel within the next 30 days. (Delta, US Airways) See all details »
$240 RT
Minneapolis, MN (MSP) No min. stay. Fare can be bought one-way for half the lowest roundtrip ... (Southwest) See all details »
$329 RT
New York City, NY (JFK) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$315 RT
New York City, NY (LGA) Lowest fare found for travel within the next 30 days. (Delta) See all details »
$323 RT
Newark, NJ (EWR) Lowest fare found for travel within the next 30 days. (United) See all details »
$304 RT
Oklahoma City, OK (OKC) Fall/Winter travel. No min. stay (American) See all details »
$251 RT
Orlando, FL (MCO) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$314 RT
Philadelphia, PA (PHL) Fall/Winter travel. No min. stay (American) See all details »
$301 RT
Philadelphia, PA (PHL) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$247 RT
Phoenix, AZ (PHX) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$303 RT
Portland, OR (PDX) Lowest fare found for travel within the next 30 days. (United) See all details »
$338 RT
Raleigh, NC (RDU) Fall/Winter travel. No min. stay (American) See all details »
$325 RT
Raleigh, NC (RDU) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$344 RT
Sacramento, CA (SMF) Lowest fare found for travel within the next 30 days. (Delta, US Airways) See all details »
$273 RT
Salt Lake City, UT (SLC) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$274 RT
San Antonio, TX (SAT) Fall/Winter travel. No min. stay (American) See all details »
$276 RT
San Diego, CA (SAN) Lowest fare found for travel within the next 30 days. (Delta, US Airways) See all details »
$326 RT
San Francisco, CA (SFO) Fall/Winter travel. No min. stay (American) See all details »
$316 RT
San Francisco, CA (SFO) Lowest fare found for travel within the next 30 days. (US Airways, American) See all details »
$266 RT
Santa Ana, CA (SNA) Lowest fare found for travel within the next 30 days. (Delta, US Airways) See all details »
$318 RT
Seattle, WA (SEA) Fall/Winter travel. No min. stay (American) See all details »
$303 RT
Seattle, WA (SEA) Lowest fare found for travel within the next 30 days. (United) See all details »
$362 RT
Tampa, FL (TPA) Fall/Winter travel. No min. stay (American) See all details »
$349 RT
Tampa, FL (TPA) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$342 RT
Tucson, AZ (TUS) Fall/Winter travel. No min. stay (American) See all details »
$322 RT
Tulsa, OK (TUL) Fall/Winter travel. No min. stay (American) See all details »
$262 RT
Washington, D.C. (DCA) Fall/Winter travel. No min. stay (American) See all details »
$235 RT
Washington, D.C. (DCA) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$356 RT
West Palm Beach, FL (PBI) Fall/Winter travel. No min. stay (American) See all details »
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