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Cheap flights to Des Moines, Iowa (DSM)

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$322 RT
Albuquerque, NM (ABQ) Late Summer/Fall travel (American) See all details »
$322 RT
Amarillo, TX (AMA) Late Summer/Fall travel (American) See all details »
$344 RT
Atlanta, GA (ATL) Non-Stop Flights. No min. stay (Delta) See all details »
$264 RT
Atlanta, GA (ATL) Lowest fare found for travel within the next 30 days. (AirTran) See all details »
$254 RT
Austin, TX (AUS) Late Summer/Fall travel (American) See all details »
$251 RT
Austin, TX (AUS) Lowest fare found for travel within the next 30 days. (United) See all details »
$358 RT
Baltimore, MD (BWI) No min. stay. No peak summer travel at this price (Delta, US Airways, United, American) See all details »
$357 RT
Baltimore, MD (BWI) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$322 RT
Birmingham, AL (BHM) Late Summer/Fall travel (American) See all details »
$344 RT
Boston, MA (BOS) No min. stay (US Airways, United, American) See all details »
$341 RT
Boston, MA (BOS) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$296 RT
Charlotte, NC (CLT) Lowest fare found for travel within the next 30 days. (United, American) See all details »
$166 RT
Chicago, IL (MDW) Non-Stop Flights. No min. stay. Fare can be bought one-way for half the... (Southwest) See all details »
$168 RT
Chicago, IL (ORD) Nonstop; Travel this weekend (United) See all details »
$165 RT
Chicago, IL (ORD) Lowest fare found for travel within the next 30 days. (United, American) See all details »
$228 RT
Corpus Christi, TX (CRP) Late Summer/Fall travel (American) See all details »
$254 RT
Dallas, TX (DFW) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$228 RT
Denver, CO (DEN) Nonstop; Travel this weekend (United) See all details »
$145 RT
Denver, CO (DEN) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$360 RT
El Paso, TX (ELP) Late Summer/Fall travel (American) See all details »
$304 RT
Ft. Lauderdale, FL (FLL) Late Summer/Fall travel (American) See all details »
$304 RT
Ft. Myers, FL (RSW) Late Summer/Fall travel (American) See all details »
$293 RT
Houston, TX (IAH) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$382 RT
Huntsville, AL (HSV) Late Summer/Fall travel (American) See all details »
$284 RT
Las Vegas, NV (LAS) Late Summer/Fall travel; Nonstop flights. No min. stay. Fare can be bou... (Southwest) See all details »
$163 RT
Las Vegas, NV (LAS) Late Summer/Fall travel; Nonstop flights. No min. stay (Allegiant) See all details »
$254 RT
Las Vegas, NV (LAS) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$254 RT
Las Vegas, NV (LAS) Late Summer/Fall travel. No min. stay (US Airways, American) See all details »
$294 RT
Little Rock, AR (LIT) Late Summer/Fall travel (American) See all details »
$316 RT
Los Angeles, CA (LAX) Late Summer/Fall travel. No min. stay. Fare can be bought one-way for h... (Southwest) See all details »
$278 RT
Los Angeles, CA (LAX) Late Summer/Fall travel. No min. stay (US Airways) See all details »
$163 RT
Los Angeles, CA (LAX) Summer travel; Nonstop flights. No min. stay. Fare can be bought one-wa... (Allegiant) See all details »
$278 RT
Los Angeles, CA (LAX) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$315 RT
Memphis, TN (MEM) Late Summer/Fall travel (American) See all details »
$320 RT
Midland, TX (MAF) Late Summer/Fall travel (American) See all details »
$349 RT
Mobile, AL (MOB) Late Summer/Fall travel (American) See all details »
$355 RT
New York City, NY (JFK) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$341 RT
New York City, NY (LGA) Lowest fare found for travel within the next 30 days. (Delta) See all details »
$328 RT
Newark, NJ (EWR) Nonstop; Travel this weekend (United) See all details »
$328 RT
Newark, NJ (EWR) Lowest fare found for travel within the next 30 days. (United) See all details »
$304 RT
Oklahoma City, OK (OKC) Late Summer/Fall travel (American) See all details »
$264 RT
Orlando, FL (MCO) No min. stay. Fare can be bought one-way for half the lowest roundtrip ... (Southwest) See all details »
$172 RT
Orlando, FL (SFB) Non-Stop Flights. No min. stay. Fare can be bought one-way for half the... (Allegiant) See all details »
$264 RT
Orlando, FL (MCO) No min. stay (Delta, US Airways, American) See all details »
$322 RT
Pensacola, FL (PNS) Late Summer/Fall travel (American) See all details »
$311 RT
Philadelphia, PA (PHL) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$247 RT
Phoenix, AZ (PHX) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$115 RT
Punta Gorda, FL (PGD) Late Summer/Fall travel; Nonstop flights. No min. stay. Fare can be bou... (Allegiant) See all details »
$339 RT
Raleigh, NC (RDU) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$339 RT
Sacramento, CA (SMF) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$262 RT
Salt Lake City, UT (SLC) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$276 RT
San Diego, CA (SAN) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$329 RT
San Francisco, CA (SFO) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$266 RT
Santa Ana, CA (SNA) Lowest fare found for travel within the next 30 days. (Delta, US Airways) See all details »
$318 RT
Seattle, WA (SEA) No min. stay. Fare can be bought one-way for half the lowest roundtrip ... (Southwest) See all details »
$283 RT
Seattle, WA (SEA) Fall/Winter travel. No min. stay. No peak holiday travel at this price (Frontier) See all details »
$138 RT
St. Petersburg, FL (PIE) Late Summer/Fall travel; Nonstop flights. No min. stay. Fare can be bou... (Allegiant) See all details »
$342 RT
Tucson, AZ (TUS) Late Summer/Fall travel (American) See all details »
$262 RT
Washington, D.C. (DCA) Late Summer/Fall travel (American) See all details »
$245 RT
Washington, D.C. (DCA) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
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