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Cheap flights to Des Moines, Iowa (DSM)

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$298 RT
Atlanta, GA (ATL) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$243 RT
Austin, TX (AUS) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$254 RT
Baltimore, MD (BWI) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$314 RT
Boston, MA (BOS) Lowest fare found for travel within the next 30 days. (United) See all details »
$246 RT
Charlotte, NC (CLT) Lowest fare found for travel within the next 30 days. (United) See all details »
$165 RT
Chicago, IL (ORD) Lowest fare found for travel within the next 30 days. (United, American) See all details »
$166 RT
Chicago, IL (MDW) Non-Stop Flights. No min. stay. Fare can be bought one-way for half the... (Southwest) See all details »
$213 RT
Dallas, TX (DFW) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$105 RT
Denver, CO (DEN) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$362 RT
El Paso, TX (ELP) Fall/Winter travel. No min. stay. No peak holiday travel at this price (American) See all details »
$362 RT
Ft. Myers, FL (RSW) Fall/Winter travel. No min. stay. No peak holiday travel at this price (American) See all details »
$360 RT
Harrisburg, PA (MDT) Fall/Winter travel. No min. stay. No peak holiday travel at this price (American) See all details »
$242 RT
Houston, TX (IAH) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$362 RT
Jacksonville, FL (JAX) Fall/Winter travel. No min. stay. No peak holiday travel at this price (American) See all details »
$197 RT
Las Vegas, NV (LAS) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$284 RT
Las Vegas, NV (LAS) Non-Stop Flights. No min. stay. Fare can be bought one-way for half the... (Southwest) See all details »
$356 RT
Lexington, KY (LEX) Fall/Winter travel. No min. stay. No peak holiday travel at this price (American) See all details »
$306 RT
Little Rock, AR (LIT) Fall/Winter travel. No min. stay. No peak holiday travel at this price (American) See all details »
$255 RT
Los Angeles, CA (LAX) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$322 RT
Lubbock, TX (LBB) Fall/Winter travel. No min. stay. No peak holiday travel at this price (American) See all details »
$362 RT
New Orleans, LA (MSY) Fall/Winter travel. No min. stay. No peak holiday travel at this price (American) See all details »
$360 RT
New York City, NY (LGA) Lowest fare found for travel within the next 30 days. (Delta) See all details »
$365 RT
Newark, NJ (EWR) Lowest fare found for travel within the next 30 days. (United) See all details »
$355 RT
Orlando, FL (MCO) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$302 RT
Philadelphia, PA (PHL) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$177 RT
Phoenix, AZ (PHX) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$253 RT
Portland, OR (PDX) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$357 RT
Raleigh, NC (RDU) Fall/Winter travel. No min. stay. No peak holiday travel at this price (American) See all details »
$330 RT
Raleigh, NC (RDU) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$400 RT
Reno, NV (RNO) Fall/Winter travel. No min. stay. No peak holiday travel at this price (American) See all details »
$344 RT
Sacramento, CA (SMF) Lowest fare found for travel within the next 30 days. (Delta) See all details »
$203 RT
Salt Lake City, UT (SLC) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$268 RT
San Diego, CA (SAN) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$294 RT
San Francisco, CA (SFO) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$266 RT
Santa Ana, CA (SNA) Lowest fare found for travel within the next 30 days. (Delta, US Airways) See all details »
$253 RT
Seattle, WA (SEA) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$362 RT
Syracuse, NY (SYR) Fall/Winter travel. No min. stay. No peak holiday travel at this price (American) See all details »
$362 RT
Tampa, FL (TPA) Fall/Winter travel. No min. stay. No peak holiday travel at this price (American) See all details »
$354 RT
Tampa, FL (TPA) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$294 RT
Tulsa, OK (TUL) Fall/Winter travel. No min. stay. No peak holiday travel at this price (American) See all details »
$262 RT
Washington, D.C. (DCA) Fall/Winter travel. No min. stay. No peak holiday travel at this price (American) See all details »
$240 RT
Washington, D.C. (DCA) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
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