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Cheap flights to Des Moines, Iowa (DSM)

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$345 RT
Atlanta, GA (ATL) Non-Stop Flights. No min. stay. No peak holiday travel at this price (Delta) See all details »
$298 RT
Atlanta, GA (ATL) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$253 RT
Austin, TX (AUS) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$259 RT
Baltimore, MD (BWI) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$310 RT
Boston, MA (BOS) Lowest fare found for travel within the next 30 days. (United, American) See all details »
$300 RT
Charlotte, NC (CLT) Lowest fare found for travel within the next 30 days. (Delta, United) See all details »
$166 RT
Chicago, IL (MDW) Non-Stop Flights. No min. stay. Fare can be bought one-way for half the... (Southwest) See all details »
$168 RT
Chicago, IL (ORD) Nonstop; Travel this weekend (United) See all details »
$165 RT
Chicago, IL (ORD) Lowest fare found for travel within the next 30 days. (United, American) See all details »
$309 RT
Dallas, TX (DFW) Non-Stop Flights. No peak holiday travel at this price (American) See all details »
$243 RT
Dallas, TX (DFW) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$228 RT
Denver, CO (DEN) Nonstop; Travel this weekend (United) See all details »
$105 RT
Denver, CO (DEN) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$396 RT
Ft. Lauderdale, FL (FLL) Fall/Winter travel. No peak holiday travel at this price (American) See all details »
$362 RT
Ft. Myers, FL (RSW) Fall/Winter travel. No peak holiday travel at this price (American) See all details »
$322 RT
Grand Rapids, MI (GRR) Fall/Winter travel. No peak holiday travel at this price (American) See all details »
$362 RT
Hartford, CT (BDL) No min. stay. Fare can be bought one-way for half the lowest roundtrip ... (Southwest) See all details »
$276 RT
Houston, TX (IAH) Nonstop; Travel this weekend (United) See all details »
$356 RT
Jacksonville, FL (JAX) Fall/Winter travel. No peak holiday travel at this price (American) See all details »
$284 RT
Las Vegas, NV (LAS) Non-Stop Flights. No min. stay. Fare can be bought one-way for half the... (Southwest) See all details »
$274 RT
Las Vegas, NV (LAS) Non-Stop Flights. No min. stay. Fare can be bought one-way for half the... (Southwest) See all details »
$254 RT
Las Vegas, NV (LAS) Fall travel (US Airways) See all details »
$223 RT
Las Vegas, NV (LAS) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$278 RT
Los Angeles, CA (LAX) No min. stay. No peak holiday travel at this price (Delta, US Airways) See all details »
$336 RT
Los Angeles, CA (LAX) No min. stay. Fare can be bought one-way for half the lowest roundtrip ... (Southwest) See all details »
$250 RT
Minneapolis, MN (MSP) Fall/Winter travel. No min. stay. Fare can be bought one-way for half t... (Southwest) See all details »
$365 RT
New York City, NY (LGA) Lowest fare found for travel within the next 30 days. (Delta) See all details »
$365 RT
Newark, NJ (EWR) Lowest fare found for travel within the next 30 days. (United) See all details »
$358 RT
Orlando, FL (MCO) Fall/Winter travel. No min. stay. No peak holiday travel at this price (Delta, US Airways, United, American) See all details »
$358 RT
Orlando, FL (MCO) Fall/Winter travel. No min. stay. Fare can be bought one-way for half t... (Southwest) See all details »
$355 RT
Orlando, FL (MCO) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$311 RT
Philadelphia, PA (PHL) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$213 RT
Phoenix, AZ (PHX) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$283 RT
Portland, OR (PDX) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$344 RT
Sacramento, CA (SMF) Lowest fare found for travel within the next 30 days. (Delta, US Airways) See all details »
$213 RT
Salt Lake City, UT (SLC) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$258 RT
San Diego, CA (SAN) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$283 RT
San Francisco, CA (SFO) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$266 RT
Santa Ana, CA (SNA) Lowest fare found for travel within the next 30 days. (Delta, US Airways) See all details »
$318 RT
Seattle, WA (SEA) Fall/Winter travel. No min. stay. Fare can be bought one-way for half t... (Southwest) See all details »
$263 RT
Seattle, WA (SEA) Fall travel. No min. stay (Frontier) See all details »
$402 RT
Tampa, FL (TPA) Fall/Winter travel. No peak holiday travel at this price (American) See all details »
$359 RT
Tampa, FL (TPA) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$262 RT
Washington, D.C. (DCA) Fall/Winter travel. No peak holiday travel at this price (American) See all details »
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