Cheap flights to Des Moines, Iowa (DSM)

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$257 RT
Atlanta, GA (ATL) Lowest fare found for travel within the next 30 days. (US Airways, American) See all details »
$281 RT
Austin, TX (AUS) Lowest fare found for travel within the next 30 days. (Delta, American) See all details »
$210 RT
Baltimore, MD (BWI) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$340 RT
Boston, MA (BOS) Lowest fare found for travel within the next 30 days. (United) See all details »
$272 RT
Burbank, CA (BUR) Lowest fare found for travel within the next 30 days. (United, US Airways, American) See all details »
$311 RT
Charlotte, NC (CLT) Lowest fare found for travel within the next 30 days. (US Airways, American) See all details »
$163 RT
Chicago, IL (ORD) Lowest fare found for travel within the next 30 days. (United, American, US Airways) See all details »
$180 RT
Chicago, IL (MDW) Lowest fare found for travel within the next 30 days. (Delta) See all details »
$274 RT
Cleveland, OH (CLE) Lowest fare found for travel within the next 30 days. (Delta, US Airways) See all details »
$321 RT
Columbus, OH (CMH) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$170 RT
Dallas, TX (DFW) Lowest fare found for travel within the next 30 days. (United) See all details »
$190 RT
Dallas, TX (DAL) Lowest fare found for travel within the next 30 days. (Delta) See all details »
$258 RT
Denver, CO (DEN) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$269 RT
Detroit, MI (DTW) Lowest fare found for travel within the next 30 days. (US Airways, American) See all details »
$291 RT
Ft. Lauderdale, FL (FLL) Lowest fare found for travel within the next 30 days. (US Airways, American) See all details »
$309 RT
Ft. Myers, FL (RSW) Lowest fare found for travel within the next 30 days. (US Airways, American) See all details »
$316 RT
Grand Rapids, MI (GRR) Lowest fare found for travel within the next 30 days. (United, US Airways, American) See all details »
$268 RT
Hartford, CT (BDL) Lowest fare found for travel within the next 30 days. (US Airways, American) See all details »
$257 RT
Houston, TX (IAH) Lowest fare found for travel within the next 30 days. (United) See all details »
$245 RT
Houston, TX (HOU) Lowest fare found for travel within the next 30 days. (American) See all details »
$223 RT
Indianapolis, IN (IND) Lowest fare found for travel within the next 30 days. (US Airways, American) See all details »
$340 RT
Jacksonville, FL (JAX) Lowest fare found for travel within the next 30 days. (US Airways, American) See all details »
$262 RT
Las Vegas, NV (LAS) Lowest fare found for travel within the next 30 days. (Delta, American) See all details »
$272 RT
Los Angeles, CA (LAX) Lowest fare found for travel within the next 30 days. (United, Delta, American, US Airways) See all details »
$232 RT
Nashville, TN (BNA) Lowest fare found for travel within the next 30 days. (Delta) See all details »
$230 RT
New Orleans, LA (MSY) Lowest fare found for travel within the next 30 days. (US Airways, American) See all details »
$236 RT
New York City, NY (LGA) Lowest fare found for travel within the next 30 days. (Delta) See all details »
$279 RT
New York City, NY (JFK) Lowest fare found for travel within the next 30 days. (US Airways, American) See all details »
$244 RT
Newark, NJ (EWR) Lowest fare found for travel within the next 30 days. (United, American) See all details »
$320 RT
Oakland, CA (OAK) Lowest fare found for travel within the next 30 days. (US Airways, American) See all details »
$298 RT
Oklahoma City, OK (OKC) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$260 RT
Ontario, CA (ONT) Lowest fare found for travel within the next 30 days. (US Airways, American) See all details »
$291 RT
Orlando, FL (MCO) Lowest fare found for travel within the next 30 days. (United) See all details »
$285 RT
Philadelphia, PA (PHL) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$227 RT
Phoenix, AZ (PHX) Lowest fare found for travel within the next 30 days. (United, American) See all details »
$269 RT
Pittsburgh, PA (PIT) Lowest fare found for travel within the next 30 days. (US Airways, American) See all details »
$271 RT
Portland, OR (PDX) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$310 RT
Raleigh, NC (RDU) Lowest fare found for travel within the next 30 days. (United, American) See all details »
$297 RT
Richmond, VA (RIC) Lowest fare found for travel within the next 30 days. (US Airways, American) See all details »
$365 RT
Sacramento, CA (SMF) Lowest fare found for travel within the next 30 days. (United) See all details »
$319 RT
Salt Lake City, UT (SLC) Lowest fare found for travel within the next 30 days. (American, US Airways) See all details »
$271 RT
San Antonio, TX (SAT) Lowest fare found for travel within the next 30 days. (American) See all details »
$282 RT
San Diego, CA (SAN) Lowest fare found for travel within the next 30 days. (United, American, US Airways) See all details »
$316 RT
San Francisco, CA (SFO) Lowest fare found for travel within the next 30 days. (US Airways, American) See all details »
$326 RT
Seattle, WA (SEA) Lowest fare found for travel within the next 30 days. (United, American) See all details »
$325 RT
Spokane, WA (GEG) Lowest fare found for travel within the next 30 days. (US Airways, American) See all details »
$201 RT
St. Louis, MO (STL) Lowest fare found for travel within the next 30 days. (United) See all details »
$306 RT
Tampa, FL (TPA) Lowest fare found for travel within the next 30 days. (United) See all details »
$340 RT
Tucson, AZ (TUS) Lowest fare found for travel within the next 30 days. (United) See all details »
$194 RT
Washington, D.C. (DCA) Lowest fare found for travel within the next 30 days. (United) See all details »
$194 RT
Washington, D.C. (IAD) Lowest fare found for travel within the next 30 days. (United) See all details »
$299 RT
West Palm Beach, FL (PBI) Lowest fare found for travel within the next 30 days. (US Airways, American) See all details »
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