Cheap flights to Des Moines, Iowa (DSM)

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$220 RT
Atlanta, GA (ATL) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$281 RT
Austin, TX (AUS) Lowest fare found for travel within the next 30 days. (Delta) See all details »
$211 RT
Baltimore, MD (BWI) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$267 RT
Boston, MA (BOS) Lowest fare found for travel within the next 30 days. (United) See all details »
$272 RT
Burbank, CA (BUR) Lowest fare found for travel within the next 30 days. (United, Delta) See all details »
$275 RT
Charlotte, NC (CLT) Lowest fare found for travel within the next 30 days. (United) See all details »
$200 RT
Chicago, IL (MDW) Non-Stop Flights.. No min. stay.. Fare can be bought one-way for half t... (Southwest) See all details »
$236 RT
Chicago, IL (MDW) Non-Stop Flights.. No min. stay.. Fare can be bought one-way for half t... (Southwest) See all details »
$199 RT
Chicago, IL (ORD) Non-Stop Flights.. No min. stay.. No peak holiday travel at this price. (United, American) See all details »
$194 RT
Chicago, IL (MDW) Lowest fare found for travel within the next 30 days. (Delta) See all details »
$168 RT
Chicago, IL (ORD) Nonstop; Travel this weekend. (United) See all details »
$194 RT
Chicago, IL (MDW) 330 day travel period.. No min. stay.. No peak holiday travel at this p... (Delta) See all details »
$279 RT
Cleveland, OH (CLE) Lowest fare found for travel within the next 30 days. (US Airways, American) See all details »
$300 RT
Columbus, OH (CMH) Lowest fare found for travel within the next 30 days. (American) See all details »
$222 RT
Dallas, TX (DFW) Lowest fare found for travel within the next 30 days. (US Airways, American) See all details »
$220 RT
Dallas, TX (DAL) Lowest fare found for travel within the next 30 days. (Delta) See all details »
$257 RT
Denver, CO (DEN) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$296 RT
Detroit, MI (DTW) Lowest fare found for travel within the next 30 days. (US Airways, American) See all details »
$299 RT
Ft. Lauderdale, FL (FLL) Lowest fare found for travel within the next 30 days. (US Airways, American) See all details »
$314 RT
Ft. Myers, FL (RSW) Lowest fare found for travel within the next 30 days. (US Airways, American) See all details »
$321 RT
Grand Rapids, MI (GRR) Lowest fare found for travel within the next 30 days. (United) See all details »
$306 RT
Hartford, CT (BDL) Lowest fare found for travel within the next 30 days. (US Airways, American) See all details »
$272 RT
Houston, TX (IAH) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$273 RT
Houston, TX (HOU) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$228 RT
Indianapolis, IN (IND) Lowest fare found for travel within the next 30 days. (United, Delta, US Airways, American) See all details »
$342 RT
Jacksonville, FL (JAX) Lowest fare found for travel within the next 30 days. (US Airways, American) See all details »
$286 RT
Las Vegas, NV (LAS) Non-Stop Flights.. No min. stay.. Fare can be bought one-way for half t... (Southwest) See all details »
$235 RT
Las Vegas, NV (LAS) Lowest fare found for travel within the next 30 days. (Delta) See all details »
$278 RT
Los Angeles, CA (LAX) Lowest fare found for travel within the next 30 days. (United, US Airways) See all details »
$276 RT
Minneapolis, MN (MSP) Lowest fare found for travel within the next 30 days. (United) See all details »
$244 RT
Nashville, TN (BNA) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$235 RT
New Orleans, LA (MSY) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$268 RT
New York City, NY (JFK) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$230 RT
New York City, NY (LGA) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$230 RT
Newark, NJ (EWR) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$313 RT
Oakland, CA (OAK) Lowest fare found for travel within the next 30 days. (US Airways, American) See all details »
$251 RT
Oklahoma City, OK (OKC) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$269 RT
Ontario, CA (ONT) Lowest fare found for travel within the next 30 days. (Delta, US Airways, American) See all details »
$275 RT
Orlando, FL (MCO) Lowest fare found for travel within the next 30 days. (United) See all details »
$267 RT
Philadelphia, PA (PHL) Lowest fare found for travel within the next 30 days. (United) See all details »
$221 RT
Phoenix, AZ (PHX) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$277 RT
Pittsburgh, PA (PIT) Lowest fare found for travel within the next 30 days. (United, US Airways) See all details »
$296 RT
Portland, OR (PDX) Lowest fare found for travel within the next 30 days. (United) See all details »
$346 RT
Raleigh, NC (RDU) Lowest fare found for travel within the next 30 days. (United) See all details »
$307 RT
Richmond, VA (RIC) Lowest fare found for travel within the next 30 days. (US Airways, American) See all details »
$365 RT
Sacramento, CA (SMF) Lowest fare found for travel within the next 30 days. (United, Delta) See all details »
$260 RT
Salt Lake City, UT (SLC) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$278 RT
San Antonio, TX (SAT) Lowest fare found for travel within the next 30 days. (United, Delta, US Airways, American) See all details »
$288 RT
San Diego, CA (SAN) Lowest fare found for travel within the next 30 days. (United, US Airways, American) See all details »
$287 RT
San Francisco, CA (SFO) Lowest fare found for travel within the next 30 days. (US Airways) See all details »
$318 RT
San Jose, CA (SJC) Lowest fare found for travel within the next 30 days. (Delta, US Airways, American) See all details »
$312 RT
Seattle, WA (SEA) Lowest fare found for travel within the next 30 days. (Frontier) See all details »
$329 RT
Spokane, WA (GEG) Lowest fare found for travel within the next 30 days. (US Airways, American) See all details »
$234 RT
St. Louis, MO (STL) Lowest fare found for travel within the next 30 days. (United, US Airways, American) See all details »
$344 RT
Tucson, AZ (TUS) Lowest fare found for travel within the next 30 days. (United, Delta, US Airways, American) See all details »
$203 RT
Washington, D.C. (DCA) Lowest fare found for travel within the next 30 days. (US Airways, American) See all details »
$214 RT
Washington, D.C. (IAD) Lowest fare found for travel within the next 30 days. (United, Delta) See all details »
$299 RT
West Palm Beach, FL (PBI) Lowest fare found for travel within the next 30 days. (US Airways, American) See all details »
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