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Cheap flights from Des Moines, Iowa (DSM)

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$306 RT	Akron, OH (CAK)	Includes all taxes. No min. stay. Fare can be bought one-way for half t... (AirTran) See all details »
$338 RT	Baltimore, MD (BWI)	Includes all taxes. No min. stay. Fare can be bought one-way for half t... (AirTran) See all details »
$269 RT	Burbank, CA (BUR)	Includes all taxes. No min. stay (United) See all details »
$200 RT	Las Vegas, NV (LAS)	Nonstop incl. all taxes. No min. stay (Allegiant) See all details »
$262 RT	Los Angeles, CA (LAX)	Nonstop incl. all taxes. No min. stay. Fare can be bought one-way for h... (Allegiant) See all details »
$259 RT	Orlando, FL (MCO)	Includes all taxes. 330 day travel period. No min. stay (Continental, United) See all details »
$212 RT	Orlando, FL (SFB)	Nonstop incl. all taxes. No min. stay (Allegiant) See all details »
$301 RT	Santa Ana, CA (SNA)	Includes all taxes (Delta, Frontier) See all details »
$324 RT	Spokane, WA (GEG)	Includes all taxes (Frontier) See all details »
$307 RT	Spokane, WA (GEG)	Includes all taxes. No min. stay (Frontier) See all details »
$229 RT	St. Petersburg, FL (PIE)	Nonstop incl. all taxes. No min. stay (Allegiant) See all details »
$271 RT	Tucson, AZ (TUS)	Includes all taxes. No min. stay (American, United, Frontier) See all details »
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